AGMATINE
AGMATINE
Agmatine is a metabolic byproduct of Arginine produced through a process called decarboxylation. Agmatine is basically Arginine with the carboxylic acid end removed. Agmatine produces the byproducts Guanidino-butyladehyde and the polyamines putruscene, spermine, and spermidine which are involved in cell growth, so it acts as a neurotransmitter and neuromodulator with a vast array of actions in the body. Agmatine promotes the release of insulin and uptake of calcium in pancreatic cells supporting healthy insulin sensitivity, and supports the release of catecholeamines assisting in stress management. Agmatine can also inhibit Nitric Oxide Synthase (NOS), specifically iNOS and nNOS, leading to increased potential muscle pumps.